DNA damage and repair in oncogenic transformation by heavy ion radiation.

Energetic heavy ions are present in galactic cosmic rays and solar particle events. One of the most important late effects in risk assessment is carcinogenesis. We have studied the carcinogenic effects of heavy ions at the cellular and molecular levels and have obtained quantitative data on dose-response curves and on the repair of oncogenic lesions for heavy particles with various charges and energies. Studies with repair inhibitors and restriction endonucleases indicated that for oncogenic transformation DNA is the primary target. Results from heavy ion experiments showed that the cross section increased with LET and reached a maximum value of about 0.02 micrometer2 at about 500 keV/micrometer. This limited size of cross section suggests that only a fraction of cellular genomic DNA is important in radiogenic transformation. Free radical scavengers, such as DMSO, do not give any effect on induction of oncogenic transformation by 600 MeV/u iron particles, suggesting most oncogenic damage induced by high-LET heavy ions is through direct action. Repair studies with stationary phase cells showed that the amount of reparable oncogenic lesions decreased with an increase of LET and that heavy ions with LET greater than 200 keV/micrometer produced only irreparable oncogenic damage. An enhancement effect for oncogenic transformation was observed in cells irradiated by low-dose-rate argon ions (400 MeV/u; 120 keV/micrometer). Chromosomal aberrations, such as translocation and deletion, but not sister chromatid exchange, are essential for heavy-ion-induced oncogenic transformation. The basic mechanism(s) of misrepair of DNA damage, which form oncogenic lesions, is unknown.     

飞机燃油油量测量及姿态误差修正方法

提出了一种基于 CAD技术的航空燃油油量实时测量方法。采用三维实体造型技术 ,建立了某飞机机翼油箱模型 ,利用油量传感器的输出值及飞机姿态信息 ,对燃油油量进行实时测量及姿态误差修正。     

High speed driving of a gain-switched laser diode with anexponential transmission line

With the increase of information capacity of an airborne system, high speed driving of laser diodes have been of interest. In order to match the low resistive LD, proposed in this paper is an exponential transmission line, which is used as preshaping to compensate the pattern effect in gain switching of laser diodes. It also will be used to overcome the effect of parasitic elements in high speed driving to improve the rise and trail edges of the output waveform. An accurate circuit model of the exponential line for the PSPICE program has been developed and simulations are conveniently carried out by employing PSPICE     

数字人感系统的研究

随着飞机模拟器技术的发展,电机伺服系统在人感系统中也得到了广泛的应用。本文着重讨论 了以DSP芯片为核心的数字人感系统组成和工作原理,并分析了系统的特点及功能。     

调制域测频原理及工程实现

介绍了调制域这一新概念，着重分析了调制域测频方法，给出了所实现的调制域测频系统框图，展示了调制域测试的关键技术、内插技术和无间隔计数技术，介绍了游标内插法，独立提出了斜波内插法和孪生链。     

淡谈空管设备维护人才的培养

长期以来，民航空管设备维护人才队伍始终受工作性质和环境的制约，存在不专、不精的问题，往往是大家业务水平相差不大，对每一类设备，或者对一类设备中的各个部分的了解程度大都在一个层面上，一般的问题大家都能解决，而疑难杂症却鲜有人能解决，这就给空管设备的安全运行带来极大的隐患。作为一个参加工作五年的空管雷达设备机务员，笔者在这里以做机务员的经历谈谈自己对空管设备维护人才培养的想法。     

中燃速HTPB推进剂燃速公差控制

研究了复合推进剂燃速公差控制的原理和方法，评估了固体组分粒度偏差和组分称量偏差地中燃速丁羟推进剂燃速公差的影响，结果表明，粒度偏差是导致燃速波动的主要原因，称量偏差的影响可忽略不计。     

阳极氧化铝模板法制备CoPt纳米管

采用电化学直流沉积,首次在氧化铝模板中成功制备出直径为50 nm的CoPt纳米管高度有序阵列。利用透射电子显微镜(TEM)、扫描电子显微镜(SEM)、X射线衍射仪(XRD)以及振动样品磁强计(VSM)对样品的结构和磁学特性进行测试。分析表明,CoPt纳米管是以面心立方(fcc)结构存在。当外加磁场与纳米线平行时,CoPt合金纳米管的矫顽力达450 Oe,这种大面积制备的CoPt纳米管希望在超高密度信息磁存储上得到应用。     

用Monte-Carlo法作Bézier曲线

本文主要内容是用Monte-Carlo法作Bézier曲线,以及Monte-Carlo法和Bézier曲线的联系。     

悬停状态下旋翼模型桨叶气弹稳定性试验研究

详细介绍了旋翼桨叶气弹稳定性试验采用的试验模型，试验设备，试验状态和试验方法。重点论述了先进旋翼的结构形式，以及简单可靠的周期变矩激振方法。试验用液压作动简对自动倾斜器的不动环激振，共进行４６种状态结果，其结果符合要求，与理论分析结果有较好的一致性。该项试验的激振方法和数据采集处理技术可直接用于直升机型号研制中的旋翼气弹稳定性试验，为进一步发展我国旋翼气弹稳定性试验技术打下了良好的基础。